Fox's hit medical-mysteries series House is mixing it up next week, and you Wilson (Robert Sean Leonard) fans are going to love the twist!

Instead of Gregory House (Hugh Laurie) being the lead investigator on a health crisis, sidekick James "Jim" Wilson is the man at the center of the show, and Celebrity Jeopardy! standout/The West Wing star Josh Malina plays the patient whom Wilson must save.

As executive producer Katie Jacobs told us earlier this year, "We have this upcoming episode where House is to Wilson as Wilson is usually to House. Like he'll be in the middle of something and House will drop by, or he'll go see House in the middle of a differential diagnosis meeting, and we'll never even know what they were working on. I'm excited about it."

For an exclusive sneak peek video of Robert Sean Leonard's star turn, which airs Nov. 30 at 8 p.m. on Fox, press play above!

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Hold on to your sofas, TV fans, because Wednesday night's 100th episode of Criminal Minds is going to be superscary! C. Thomas Howell is back as George "The Reaper" Foyet, and he's got Hotch's (Thomas Gibson) family in his evil clutches. Honestly, we're not sure that Haley (Meredith Monroe) is going to make it. Eek!

Press play above to see J.J. (A.J. Cook) defend Hotch to that mean lady who runs the BAU division of the FBI, and then click in for three more sneak peeks of Wednesday night's craziness!

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Awww...poor Nate! He's got a crush on Serena, and she's entangled with Trip, and oh, what a tangled love-triangle web these Upper East Siders weave! Will Serena see the light? Will Nate have a happy Thanksgiving? Is Trip even sexy enough to be a part of this circle? These and other burning questions answered, next Monday on Gossip Girl!

Plus, wanna see Chuck behave like a big brother (again!), and Lily ruin Thanksgiving for her family? Click in...

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This week's all-new installment of Glee is called "Ballad," and it centers on Rachel Berry's (Lea Michele) new and inappropriate crush on "Mr. Shu" (Matthew Morrison). As Mr. Shu tries to manage Rachel's feelings, he recalls another schoolgirl-crush situation that plagued him in the past. And that young lady is none other than the always-divine Sarah Drew as Suzy Pepper. We caught up with Sarah a few weeks back to discuss her guest gig on Grey's Anatomy and she tipped us off about what to expect from her Glee part:

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Heather Locklear really does have something goin' on. Maybe it's her 30 years of experience in series television or maybe it's that her boobs look fantastic, but whatever the source of power, Locklear's ability to transform TV shows appears to remain entirely intact.

Heather Locklear (re)joins the cast of Melrose Place this coming Tuesday, and it looks like she still has exactly the chilly authority the CW needs to up Melrose's profile in TV land. Melrose's prospects remain realistically dim, but should Heather's arrival generate enough buzz and a moderate ratings increase, the show might live out the season and be considered for a second year. It's hard to tell what people really want from their nighttime soaps, so who's to say why the show is struggling, but Locklear's involvement is as likely as any other effort to bring about a series renewal.

Now, as for the content of these three sneak peeks, Amanda's definitely moving in to Ella's (Katie Cassidy) PR firm, but where will she live now that she's back in town? Find out:

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Remember that knife the cops found last week on Melrose Place? Well, according to the sneak peek above from Tuesday's all-new episode, Auggie's prints are all over it! Could our nearly departed Colin Egglesfield be playing the killer after all? The evidence says yes, but after watching this sneak peek, we're beginning to wonder about Katie Cassidy's conniving Ella. She's definitely up to something. And then there's ol' crazy eyes herself, Violet (Ashlee Simpson-Wentz), who is, of course, named in the Melrose Place yearbook as Resident Most Likely to Be a Homicidal Maniac. 

Not interested in solving the Melrose murder mystery? Well in that case, we've also got some romance for you!

Click in to get your first look at the steamy liplock between delish duo Lauren (Stephanie Jacobsen) and David (Shaun Sipos).

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Whoo! "Wheels" is almost here. The much-talked-about and heartbreakingly good Glee episode "Wheels" premieres Wednesday at 9 p.m. on Fox, but we have five sneak peeks for you right here, right now, to get you excited about what's to come. Up first? Press play above to see the beginning of the "diva-off" between Rachel (Lea Michele) and Kurt (Chris Colfer) over the Wicked song "Defying Gravity."

Want to hear the diva-off before it airs on TV? YouTube has you covered—and Lea and Chris do a beautiful job (listen with Kleenex close at hand)—but unless you are absolutely rabid for Glee spoilers, we recommend you wait to experience this song as part of the overall episode.

Ready for more "Wheels"? Click in for four sneak peeks, including an early look at Artie's solo (Kevin McHale) and Mr. Shu's (Matthew Morrison) crafty plan to teach the kids a little something about tolerance...

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Bianca in Palm Beach, Fla.: OMFG! Please help! I am now just hearing of this ridiculous complaint that the Parent Television Council is making against next Monday's episode of Gossip Girl, because of the threesome storyline. I hope this is just for publicity, but can you reassure us that the episode will indeed air? Please?! Thank youuu!!!

In case you haven't heard, TV fans, the self-appointed band of media moralizers known as the Parents Television Council has gotten wind of the Gossip Girl threesome set for this coming Monday, and boy, are their granny panties in a bunch! The PTC is sending sternly worded faxes hither and yon in protest, but does this squawky bunch of cultural conservatives actually have any power?

Could they be persuading the CW to step back from the threesome storyline? We've done a little digging and here's the word on the street:

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Spoiler Alert! Could yet another OMFG moment be on the way to Gossip Girl?

First we break the news that Bart Bass (Robert John Burke) is coming back.

And now, this is just a crazy unconfirmed theory, but: Could Olivia (Hilary Duff) be pregnant?!

One peek at the footage above from next week's Gossip Girl and you'll see:

1. Olivia and Dan are spending a lot of time doing the dirty.
2. Naked. Between the sheets.
3. According to Quinn Fabray on Glee, it takes far less than that to make a baby.
4. Olivia mentions she is craving ice cream! (OK, gelato, but we hear that's a similar specimin for glamorous prego types.)

OK, so that's probably totally not true. Olivia is not pregnant. But still, stranger things have happened on this show (see: Bart Bass). And regardless, the Duffster sure seems to be hiding a lot. Can Dan take it?

Meanwhile, Blair and Serena are totally breaking up, and trading up. See for yourself in the clips below...

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This is so cute. Meredith Grey is out of commission (officially because she donated an organ to her daddio, unofficially because Ellen Pompeo was having a kid), so not only is Patrick Dempsey's Dr. Derek Shepherd getting the lead-character spotlight to himself this week on Grey's Anatomy, he's getting the voice-over!

Pompeo does the Anatomy voice-over the overwhelming majority of the time, but now and again the spotlight shifts to another character's point of view.

This week Dempsey takes the lead, as Derek faces down an inoperable supertumor that has the hospital aflutter with excitement and as the Chief (James Pickens Jr.) feels increasingly threatened by McDreamy's surgical confidence and administrative prowess.

Click in for four more early looks at the Dempsey goodness!

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Enough about vampires for the moment—let's talk about aliens instead.

Check out this extended sneak peek of Elizabeth Mitchell's new epic sci-fi series V, which is based on the 1983 miniseries of the same, and which premieres on ABC on Nov. 3 at 8 p.m.

Some early thoughts:

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Courtesy AP Images / Casey Rogers

Hear that?

Bom-chicka-bow-wow... 

It's the sound of Jack Donaghy (Alec Baldwin) and Liz Lemon (Tina Fey) finally hooking up…in a hot and steamy porno scene, no less!

The only glitch? It's not exactly Jack and not exactly Liz, but it is a sexy version of the two that goes down (courtesy of a porno Tracy Jordan shoots) in the second episode of 30 Rock's new season, and it is guaranteed to make you fans laugh out loud.

Season three of the Rock launches tonight—holler!—and we've chatted up executive producer Robert Carlock for the scoop on what big things he's planning.

For starters we have a big ol' warning for Betty White:

Don't look now, but we think Tracy Jordan is totally trying to kill you!

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